NEWS ARCHIVE 2005-2019!
Infosys Prize for G. Mugesh - News Item in Angewandte Chemie
The Infosys Science Foundation has announced its prize winners for 2019 in six categories. The Infosys Prize for Physical Sciences is awarded to Govindasamy Mugesh (Indian Institute of Science, Bangalore) in recognition of his work on the synthesis of small molecules and nanomaterials for biomedical applications....
Namrata Singh receives the IIT Bombay Metrohm Young Chemist Award
Namrata Singh has been awarded the IIT Bombay Metrohm Young Chemist Award 2019 for "Innovation in Research" at an award ceremony held at IIT Bombay on September 17, 2019. The award was given for her research on uncovering the role of an antioxidant nanozyme that provides cytoprotection in Parkinson’s Disease model.
Highlight on the Cover Page of Chemistry - A European Journal
Our paper published in collaboration with Dr Kenta Arai and Prof. Michio Iwaoka on "Modeling Thioredoxin Reductase‐Like Activity with Cyclic Selenenyl Sulfides: Participation of an NH⋅⋅⋅Se Hydrogen Bond through Stabilization of the Mixed Se−S Intermediate" is highlighted on the Cover of Chemistry - An European Journal.
“Reviews Showcase” in Chemistry - A European Journal
Our recent concept article on Directing Traffic: Halogen-Bond-Mediated Membrane Transport has been selected by the Editorial Office for the Showcase of outstanding Review-type articles in Chemistry - A European Journal. In this article, we describe a novel strategy involving halogen bonding for increasing the cellular uptake of small molecules and proteins.
“Hot Paper” in Chemistry - A European Journal
Our new paper on modelling the inhibition of selenoproteins by small molecules using cysteine and selenocysteine derivatives has been selected as a "Hot Paper" in Chemistry - A European Journal. We demonstrate, for the first time, that the arylselenium species eliminated from the selenocysteine derivatives exhibit significant redox activity, which may have a significant effect on the cellular redox state during the inhibition of selenoproteins.
“Hot Paper” in Angewandte Chemie
Our new paper on membrane transport of green fluorescent protein in mammalian cells has been selected as a "Hot Paper" in Angewandte Chemie. We show that the introduction of an iodine atom to one of the tyrosine residues facilitates the cellular entry of green fluorescent proteins, providing a strategy for the delivery of macromolecules into mammalian cells.
In a first, IISc team directly delivers protein into cells - The Hindu
In a breakthrough that might have huge medical implications, researchers at Bengaluru’s Indian Institute of Science (IISc) have used a novel strategy to directly deliver proteins into mammalian cells. Proteins are big molecules and so cannot enter the cells on their own. So a team from IISc substituted a hydrogen atom of the protein with an iodine atom to achieve a nearly sixfold increase in protein uptake by cells.
ChemistryViews: Halogen-Mediated Transport through Cell Membranes
Our work on Halogen-Mediated Membrane Transport, published in Chemistry - A European Journal has been featured on ChemistryViews, Wiley-VCH's chemistry portal. We found that the introduction of iodine atoms into a series of fluorescent molecules (example pictured) remarkably enhances the cellular uptake. Using two iodine atoms, the cellular uptake can be increased to more than 95 % in mammalian cells.
Namrata Singh has been awarded an ACS Poster Prize at the CRSI-NSC-24
Namrata Singh has been awarded an ACS poster prize for her work titled "A manganese-based nanozyme for cellular redox regulation", at the 24th CRSI National Symposium in Chemistry (NSC-24), at CLRI, Chennai, during February 8 - 10, 2019.
“Very Important Paper (VIP)” in Chemistry - A European Journal
According to the evaluation of referees, our paper titled "Halogen-Mediated Membrane Transport: An Efficient Strategy for the Enhancement of Cellular Uptake of Synthetic Molecules", has been designated as Very Important Paper (VIP). Less than 5% of the manuscripts accepted for publication in the journal receive such a positive review.
Punarbasu Roy has been awarded a Poster Prize at the I-DEC-2018
Punarbasu Roy has been awarded a poster prize (RSC-Chem.Comm.) for his work titled "Mechanistic investigation of GPx-like activity of V2O5 nanozyme", at the Inter-Disciplinary Explorations in Chemistry (I-DEC-2018) at IISER Bhopal, during December 6 - 8, 2018.
Author Profile in Angewandte Chemie
“When I was eighteen I wanted to be a farmer. The natural talent I would like to be gifted with is the ability to learn new languages quickly …” Find out more about Govindasamy Mugesh in his Author Profile.
ACS Chemical Biology - Introducing Our Authors
ACS Chemical Biology showcases the graduate students who contributed significantly to their first paper in the "Introducing Our Authors" section of the journal. The profiles of NaveenKumar, S. K. and SharathBabu, B. N., have been featured in the August 2018 issue of ACS Chemical Biology.
Making cellular probes more effective - BusinessLine
Scientists at Indian Institute of Science, Bengaluru have found a way to enhance uptake of fluorescent probes into cells. They have found that by replacing hydrogen atoms at crucial places of napthalimide with iodine or bromide atoms makes it easier to break into cells.
Iodine Magic - A highlight of our recent work in The Hindu
Studying the uptake of thyroid hormone may become easier - Fluorescent probes are routinely used for studying drug delivery, membrane activity and cellular functions. By substituting two hydrogen atoms of a commonly used fluorescent probe (naphthalimide) with iodine, researchers at the Indian Institute of Science (IISc), Bengaluru, have been able to increase the cellular uptake of the probe molecule from 5-8% to 98%.
Sourav Ghosh has been awarded a Poster Prize at the CRSI-NSC-23
Sourav Ghosh has been awarded a poster prize for his work titled "Nanoisozymes: Crystal-Facet-Dependent Enzyme-Mimetic Activity of V2O5 Nanomaterials," at the 23rd CRSI National Symposium in Chemistry (NSC-23) at IISER Bhopal, during July 13 - 15, 2018.
Namrata Singh Wins a Poster Prize at Gordon Research Conference
Namrata Singh has been awarded a poster prize for her work on "An antioxidant nanozyme providing cytoprotection in Parkinson’s Disease Model," at the Gordon Research Conference “Metals in Medicine” organized in Proctor Academy, New Hampshire, USA, during June 24 - 29, 2018. The poster has also been selected for a Poster Slam.
IISc team synthesizes artificial enzyme
Nanozyme mimics the antioxidant enzyme glutathione peroxidase - Nanomaterials that can behave like human enzymes have now been successfully synthesized by a team of researchers from Indian Institute of Science (IISc), Bengaluru. They produced the new nanozyme — nanomaterial with enzyme-like activity — by using vanadium pentoxide nanocrystals of just 150-200 nm size.
Prof. R.C. Mehrotra Commemoration Lecture Award of ISCA
Mugesh has been selected for Prof. R.C. Mehrotra Commemoration Lecture Gold Medal of the Indian Science Congress Association (ISCA) for the year 2018-19. He has been invited to deliver the Award Lecture at the 106th Indian Science Congress to be held during January 3-7, 2019.
Highlight of our work on Mn3O4 nanozyme in "The Hindu" Newspaper
A team of researchers from the Indian Institute of Science (IISc) Bengaluru has fabricated a metal oxide nanomaterial that is capable of mimicking all three major cellular antioxidant enzymes, thereby controlling the level of reactive oxygen species (ROS) inside cells. Based on in vitro test results, the nanomaterial appears a promising candidate for therapeutic applications against oxidative stress-induced neurological disorders, particularly Parkinson’s.
“Hot Paper” in Angewandte Chemie
Our new paper on redox modulatory Mn3O4 nanozyme with multi-enzyme activity has been selected as a "Hot Paper" in Angewandte Chemie. The nanozyme functionally mimics three major antioxidant enzymes - superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) - and the activity is size as well as morphology-dependent. The nanomaterial provides efficient cytoprotection to human cells in Parkinson's disease model.
Mugesh has been elected as the President of ACES
Mugesh has been elected as the President of the Asian Chemical Editorial Society (ACES) for a four-year term starting from 2018. ACES is an organization of 13 major chemical societies in the Asia-Pacific region, which publishes three international research journals: Chemistry – An Asian Journal, Asian Journal of Organic Chemistry (AsianJOC), and ChemNanoMat.
National Prize for Research on Interfaces of Chemistry and Biology
Mugesh has been selected for the National Prize for Research on Interfaces of Chemistry and Biology, awarded by C. N. R. Rao Education Foundation and JNCASR, Bangalore. The award is supported by the AVRA Laboratories Pvt. Ltd., Hyderabad. The award was conferred on him at an award ceremony held on June 5, 2017 at JNCASR, Bangalore.
Mugesh has been selected for the Bhagyatara Award 2016
Mugesh has been selected for the Bhagyatara Award for the year 2016. The award was conferred on him at an award ceremony at Panjab University on April 21, 2017. The award is given annually to an Indian scientist, who has made significant contributions in Applied Science and is actively engaged in research in the University or a research institute in India in the area of Organic Chemistry, Biochemistry or Pharmaceutical Chemistry.
Mugesh has been selected for the Rajib Goyal Prize
Mugesh has been selected for the Rajib Goyal Prize in Chemical Sciences by Kurukshetra University for the year 2014-15. The award was conferred on him at an award ceremony on April 11, 2017 at Kurukshetra University. These prizes are instituted to honour Indian scientists who are engaged in advanced research in basic and applied sciences.
Mugesh has been invited to join the Asian Chemical Biology Initiative
Mugesh has joined the Asian Chemical Biology Initiative (ACBI) as a member. This iniative is supported by the JSPS Core-to-Core Program, Japan and around 90 chemical biology professors from Japan, Korea, China, Singapore, UAE, India, New Zealand and emerging countries serve as the members.
Mugesh joins the Editorial Board of Biological Chemistry
G. Mugesh has joined the Editorial Board of Biological Chemistry, published by De Gruyter, Germany. The journal was established by Felix Hoppe-Seyler, a pioneer of Biochemistry and Molecular Biology, in 1877 and was edited by him until 1895. The journal was subsequently edited by the Nobel laureate, Albrecht Kossel, until 1927.
Amit A. Vernekar wins ASDF Best Scientific Researcher Award
Amit A. Vernekar has been selected for the "ASDF Best Scientific Research Award" for the year 2016 by the Association of Scientists, Developers and Faculties (ASDF International). The results of 6th ASDF Global Awards 2016 have been declared in a press conference held on December 09, 2016 at Michigan, USA. The winners were selected from 9877 nominations.
Highlight on the Cover Page of Organic & Biomolecular Chemistry
Mammalian selenoenzymes, iodothyronine deiodinases (DIOs), catalyze the tyrosyl and phenolic ring deiodination of thyroid hormones (THs) and play an important role in maintaining the TH concentration throughout the body. These enzymes also accept the decarboxylated thyroid hormone metabolites, iodothyronamines (TAMs), as substrates for deiodination.
Mugesh receives the Shanti Swarup Bhatnagar Prize for the year 2012
Mugesh received the S. S. Bhatnagar Prize for the year 2012 from Dr Harsh Vardhan, Union Minister for Science & Technology on the CSIR Foundation Day Platinum Jubilee Function held on 26th September 2016 at Vigyan Bhawan, New Delhi. The award function was inaugurated by the Prime Minister of India, Shri Narendra Modi.
IISc’s war on India’s killers: Cancer, CVD
A major research in the Indian Institute of Science (IISc) will target destroying the very heart of the leading cause of mortality in India – cardiovascular diseases (CVD). IISc researchers are looking at developing an oral medication to be taken by CVD patients at the very onset of the condition, not only to prevent any further damage, but cure the patient completely.
Highlight of our Review on the Cover Page in Angewandte Chemie
Our recent review on "Chemistry and Biology in the Biosynthesis and Action of Thyroid Hormones" in Angewandte Chemie has been featured on the front Cover Page. This review describes the biosynthesis, transport, metabolism, and mechanism of action of thyroid hormones, as well as thyroid-related disorders.
Mugesh joins the Editorial Advisory Board of ACS Omega
Mugesh has been invited to join the inaugural Editorial Advisory Board of ACS Omega, published by the American Chemical Society. ACS Omega is a new open-access publication for chemists, materials scientists, biologists, physicists, engineers and other researchers, that focuses on research with connections to chemistry.
Mugesh joins the Editorial Board of Organic & Biomolecular Chemistry
Mugesh has been invited to join the Editorial Board of Organic & Biomolecular Chemistry, published by the Royal Society of Chemistry (London). This is a weekly journal for the publication of highly significant original research and reviews in all areas of organic chemistry, including organic synthesis, physical organic chemistry, supramolecular chemistry and bioorganic chemistry.
Santanu Mondal Wins the Chemistry Letters Best Poster Prize
Santanu Mondal has been awarded the Chemistry Letters (Chemical Society of Japan) best poster prize at the 13th International Conference on the Chemistry of Selenium and Tellurium (ICCST-13), organized by Gifu University, Gifu, Japan during May 24-27, 2016. He received this prize for his poster titled "Selenium-mediated dehalogenation of thyroid hormones and halogenated nucleosides".
Amit A. Vernekar wins the Best Thesis Award
Amit A. Vernekar has been awarded Prof. S. Soundararajan Medal (best thesis award) for the academic year 2015-16. His thesis work describes the application of nanomaterials for biomedical applications. Amit has developed a V2O5-nanozyme that can protect human cells from oxidative damage.
Santanu Mondal Wins the ACS Chemical Biology Best Poster Prize
Santanu Mondal, a Ph.D. student working in Mugesh's laborotory, has been awarded the ACS Chemical Biology best poster prize at the International Symposium on Chemical Biology and Drug Discovery (ISCBDD-2016), organized by the National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, Bose Institute, Kolkata, and Chemical Biology Society (CBS), India during March 1-3, 2016.
Tandrila Das Wins the RSC Best Poster Prize at ICMG-2016
Tandrila Das, an undergraduate student working in Mugesh's laborotory, has been awarded the Royal Society of Chemistry (RSC) best poster prize for her poster titled "Vacancy-Engineered Nanoceria: Enzyme Mimetic Hotspots for the degradation of Nerve Agents" at the 6th International Conference on Metals in Genetics, Chemical Biology and Therapeutics (ICMG-2016), held at IISc Bangalore, during February 17-20, 2016.
A nanomaterial that can help in degrading nerve damaging chemicals
A team from IISc has found a material which can be used to degrade the toxic chemicals that inhibit the function of an enzyme, Acetylcholinesterase, which is involved in the breakdown of the nerve transmitter acetylcholine. This in turn can lead to nerve damage, paralysis and even death. Antidotes are available for nerve agent poisoning, but they do not act on the nerve agent itself – they act either on Acetylcholinesterase enzyme or its receptor.
Most Active Nanozyme
Nanozymes – enzyme mimetics based on nanomaterials – have potential applications in imaging, diagnostics, and therapeutics, although tuning their activity for specific applications by tailoring their chemical and physical properties remains a challenge. Govindasamy Mugesh and co-workers at the Indian Institute of Science, Bangalore, used a simple co-precipitation method in the presence of base to synthesize a MnFe2O4 nanomaterial.
Mugesh has been elected as Vice President of ACES
Mugesh has been elected as Vice President of the Asian Chemical Editorial Society (ACES), an organization of 13 major chemical societies in the Asia-Pacific region. ACES publishes three international research journals: Chemistry – An Asian Journal, Asian Journal of Organic Chemistry (AsianJOC), and ChemNanoMat.
Highlight of our recent research in the IISc magazine CONNECT
G Mugesh’s laboratory works on developing new therapeutic agents to battle diverse diseases like cancer, renal disease, and neurodegenerative disorder such as Alzheimer's and Parkinson's. These disorders are associated with reactive oxygen species (ROS) - chemically reactive molecules containing oxygen that are important in cell signaling - and oxidative stress......
G. Mugesh has been awarded the J.C. Bose National Fellowship
G. Mugesh has been awarded the prestigious J.C. Bose National Fellowship by the Science and Engineering Research Board, Department of Science and Technology, Government of India, for his work in the area of chemical biology, particularly for his contributions to mechanistic investigations of thyroid hormone action, enzyme mimetic antioxidants and nanomaterials for biomedical applications.
Highlight in Angewandte Chemie
Form and substance: Through observation and careful follow-up on polymorphic forms of thyroxine, Mondal and Mugesh have provided a stunningly simple answer to the apparent non-equivalence of thyroid hormone tablets. A highlight by Prof. Ulrich Schweizer and Prof. Clemens Steegborn in Angewandte Chemie on our recent work on Thyroxine Conformations.
A Spotlight in Chemistry - A European Journal
Chemistry - A European Journal Spotlights section features a selection of the excellent work that has recently been published in the sister journals. Recently, our work on the structure of thyroxine published in Angewandte Chemie (dx.doi.org/10.1002/anie.201505281) has been highlighted in this section.
Why Hypothyroidism Drugs Act up - The New Indian Express
When patients switch brands of their drug for hypothyroidism, they receive either too much or too little of this life-saving hormone. Dr Govindasamy Mugesh’s laboratory at the Department of Inorganic and Physical Chemistry, Indian Institute of Science, has recently come up with an explanation for this highly variable therapeutic property of generic thyroxine between brands.
IISc’s breakthrough in hypothyroidism treatment - Bangalore Mirror
Over 200 million people suffer from thyroid hormone deficiencies or hypothyroidism - a condition that manifests as mental slowness, depression, fatigue and weight gain. The condition is treated using synthetic thyroxine that is administered as tablets available from a variety of brands. However, different brands of synthetic thyroxine have been found to be highly variable from each other.
Highlight in Angewandte Chemie
Se-ing and doing: Isoselenazoles are novel, very potent antioxidant derivatives offering remarkable cytoprotection to human cells. Synthetically available in only a few steps, these compounds have the potential to fight diseases caused by oxidative stress. A highlight by Prof. Thomas Wirth in Angewandte Chemie on our recent work on Glutathione Peroxidase and Peroxiredoxin Mimetics.
Antioxidant panaceas: Isoselenazoles protect cells from oxidative stress
Panacea, the Greek goddess of universal remedies, is also the name given to any chemical that can supposedly cure all ailments – for example, antioxidants. Since many diseases are either caused by or exacerbated by oxidative stress, the use of antioxidants as therapeutic agents is logical. Novel antioxidants, are several more compounds called isoselenazoles that have been synthesised by a team of scientists from the Indian Institute of Science.
K. Raja wins SBIC/ICBIC17 Student Travel Award
K. Raja has been selected for the student travel award by the Society of Biological Inorganic Chemistry (SBIC) to participate in the ICBIC17 at Beijing during July 20-24, 2015. The selection by the committee was based on the submitted abstract and the quality of the applicant.
Amit A. Vernekar is one of the Finalists of the Reaxys PhD Prize
Amit A. Vernekar has been selected as one of finalists of the 2015 Reaxys PhD prize. The Reaxys PhD Prize recognizes young chemists conducting original and innovative research in organic, organometallic and inorganic chemistry. The finalists will present their research at the 2015 Reaxys PhD Prize Symposium, September 7-8, 2015, in Hong Kong.
Replacement of single atom alters thyroid biochemical cascade
More than 200 million people worldwide suffer from thyroid related disorders like hyperthyroidism, hypothyroidism, goitre, Hashimoto’s thyroiditis, thyroid cancer etc. Most of these are treated with synthetic form of T4 for hypothyrodism and thiouracil-based drugs for hyperthyroidism. However, small variations in the drug concentration can lead to adverse effects.
Debasish Bhowmick's Paper is a VIP in Angewandte Chemie
Debasish Bhowmick's article titled "Highly Efficient Glutathione Peroxidase and Peroxiredoxin Mimetics Protect Mammalian Cells against Oxidative Damage" a Very Important Paper (VIP) in Angewandte Chemie. Less than 5% of the manuscripts receive such a positive evaluation.
Amit A. Vernekar wins the GYTI Award
Amit A. Vernekar has been awarded the prestigious Gandhian Young Technological Innovation (GYTI) award for the year 2015 for his work on “Novel nanozyme technology for combating oxidative stress related disorders”. He is one of the 17 students selected for this award from over 1700 nominations in 50 technology domains.
Amit A. Vernekar wins the BVS2015 Oral Presentation Prize
Amit A. Vernekar has been awarded BVS2015 Oral Presentation Prize (First Prize) at the 4th Bharatiya Vigyan Sammelan-Youth Oriented, at Goa. This event was organized to provide a platform for the youth and around 414 abstracts were received. Prizes were awarded to the submissions that had potential for research in the future.
Hot Paper in Chemistry - A European Journal
The paper from the work of Debasish Manna and Santanu Mondal titled "Halogen Bonding Controls the Regioselectivity of the Deiodination of Thyroid Hormones and their Sulfate Analogues", published in Chemistry - A European Journal has been selected as Hot Paper by the Editors of the Journal. The main conclusion drawn from this study is that the halogen bonding is one of the crucial factors that control the regioselectivity.
IISc: novel way to reduce cell damage found
Preliminary studies have shown that vanadia nanowires can reduce cell damage and blunt the effect of one of the factors responsible for the onset of several diseases such as cancer, diabetes, cardiovascular diseases and ageing. Vanadia nanowires functionally mimic a major antioxidant enzyme in mammalian cells by using cellular thiols. The results were published in the journal Nature Communications.
Debasish Manna wins Lilly Outstanding Thesis Award
Debasish Manna has been awarded the Eli Lilly and Company Asia Outstanding Thesis Award for the year 2014. These awards are given to students who made significant contributions in the field of medicinal chemistry, organic synthesis, computational chemistry, structural biology or analytical chemistry.
Mugesh receives Dr R. A. Mashelkar Endowment Lecture Award
G. Mugesh has received "Dr. R.A. Mashelkar Endowment Lecture Award" in Advanced Materials from the National Chemical Laboratory (NCL), Pune. He delivered the endowment lecture on August 11, 2014 at NCL, Pune.
Santanu Mondal receives Best Poster Award
Poster titled "Deiodination of Thyroid Hormones and Iodothyronamines by Iodothyronine Deiodinase Mimics" by Santanu Mondal at the 5th Annual Meeting of the Proteomics Society of India on "Medical Proteomics" during November 28-30, 2013, has received the "Best Poster Award".
Mugesh receives "Asian Rising Star" commemorative plaque
G. Mugesh has been invited by the Federation of Asian Chemical Societies (FACS) to deliver a lecture in the "Asian Rising Stars" special session dedicated to young scientists at the 15th Asian Chemical Congress (ACC) during August 19-23, 2013 in Singapore. He has received a Commemorative plaque from Professor Ei-ichi Negishi, Nobel Laureate in Chemistry during the ACC.
Debasish Bhowmick wins best poster award at ICCST-12
Poster titled "Role of Steric and Electronic Effects on the Glutathione Peroxidase Activity of Amine-based Diaryl Diselenides", presented by Debasish Bhowmick at the 12th International Conference on the Chemistry of Selenium and Tellurium (ICCST-12) at Cardiff University, UK, during July 22-26, 2013, received the Best Poster Award.
Amit A. Vernekar wins best poster award at Indo-US Symposium
Poster titled "Production of Graphene, Noncovalent Functionalization and its Remarkable Antioxidant Enzyme-like Characteristics", presented by Amit A. Vernekar at the Indo-US Symposium on "Molecular Materials" at IISc, Bangalore, during July 15-17, 2013 received the Best Poster Award.
Amit Vernekar wins best poster award at Materials Genome Conference
Poster titled "Remarkable Peroxynitrite Scavenging Activity of Hemin Functionalized Graphene Nanosheets", presented by Amit A. Vernekar at the First National Conference on Mapping the "Materials Genome" at Shiv Nadar University, Dadri, during March 8-10, 2013 received the Best Poster Award.
Debasish Manna selected for the 63rd Lindau Nobel Laureate Meeting
Debasish Manna has been selected to participate in the 63rd Lindau Nobel Laureate Meeting to be held during June 30-July 05, 2013, in Lindau, Germany. In these meetings, several Nobel Laureates meet the next generation of scientists: undergraduates, PhD students, and post-doc researchers from all over the world.
Amit A. Vernekar wins best poster award at NSC-15
Poster titled "Peroxynitrite Reductase and Isomerase Activities of Graphene-Hemin Hybrid Nanosheets", presented by Amit A. Vernekar at the 15th CRSI National Symposium in Chemistry (NSC-15) at Banaras Hindu University, Varanasi, during February 1-3, 2013 received the Best Poster Award.
Mugesh wins Shanti Swarup Bhatnagar Prize 2012
G. Mugesh has been selected for the Shanti Swarup Bhatnagar Prize in Chemical Sciences for the year 2012, in recognition of his original contributions to the understanding of the thyroid hormone action and metallo-beta-lactamase-induced antibiotic resistance through the creative application of inorganic and organic chemistry.
IIT Bombay - Best Review Paper Award
One of G. Mugesh's papers titled "Heteroatom-directed Aromatic Lithiation: A Versatile Route to the Synthesis of Organochalcogen Compounds" has received the IIT Bombay Best Review Paper Award for the year 2011. This accounts, published during Ph.D. at IITB with Prof. H. B. Singh, was selected based on 10-years citation data.
News & Views in Nature Chemistry
Enzyme Mimics: Halogen and chalcogen team up. P. Metrangolo and G. Resnati write about our work published in JACS on role of cooperative chalcogen and halogen bonding in thyroid hormone metabolism in News & Views section of Nature Chemistry.
Debasish Manna wins Best Poster Prize at Eurasia Conference
Poster titled "Deiodination of Thyroid Hormones by Iodothyronine Deiodinase Mimics: Role of Chalcogen and Halogen Bonding", presented by Debasish Manna at the 12th Eurasia Conference on Chemical Sciences (EuAsC2S-12) at Corfu, Greece, during Apr. 16-21, 2012 received the Best Poster Award.
Devappa Lamani and Debasish Bhowmick win Best Poster Prize
Poster titled "Synthesis, Characterization, and Antioxidant Activity of Spirodiazaselenurane and its Derivatives", presented by Devappa Lamani and Debasish Bowmick at the "14th National Symposium in Chemistry" at NIIST, Trivandrum, during Feb. 3-5, 2012 received the Best Poster Award from the Chemical Research Society of India.
Mugesh wins AstraZeneca Excellence in Chemistry Award
G. Mugesh is awarded the AstraZeneca Excellence in Chemistry Award for the year 2011. This global award is given to talented young researchers who have demonstrated distinct achievements in synthetic, computational, mechanistic or bioorganic chemistry.
Mugesh has been elected as Fellow of the Indian Academy of Sciences
G. Mugesh has been elected as Fellow of the Indian Academy of Sciences. The Academy, founded in 1934, is one of the three major science academies in India, which aims at promoting the progress and upholding the cause of science in pure and applied branches.
Santanu Mondal receives best poster award
The poster titled "Binding of Thyroid Hormones to Transport Proteins", by Santanu Mondal at the "Diamond Jubilee Symposium on Recent Trends in Chemistry" at IIT Kharagpur during October 21-23, 2011, has received the "Best Poster Award".
IIT Bombay Best Research Paper Award
G. Mugesh has received the IIT Bombay Best Research Paper Award for the year 2010 for his publication titled "Glutathione Peroxidase-like Antioxidant Activity of Diaryl Diselenides: A Mechanistic Study". This paper, published during Ph.D. at IITB, was selected for this award based on 10-years citation data.
Bangalore scientists inch closer to a cure for "thyroid"
A group of scientists at the Indian Institute of Science (IISc) is attempting to develop new drug molecules that could combat hyperthyroidism. Encouraged by success with the synthesis of a new molecule, the researchers are now looking at ‘analogues’, which work more efficiently under normal conditions. "We are using chemicals available in the market," said G. Mugesh, associate professor at the department of inorganic and physical chemistry.
Tamilselvi wins Best Poster Award
The poster titled "Hydrolysis of Cephalosporins: Effect of Heterocyclic Thiols Eliminated During the Hydrolysis of Cephalosporins on Metallo-b-Lactamase and Peroxidase Activities", presented by A. Tamilselvi at the Symposium on Advanced Biological Inorganic Chemistry, TIFR, Mumbai, has received the "Best Poster Award".
Bangalore scientists may hold key to taming diabetes enzyme
Apetulant, wild enzyme blamed for triggering a host of killer diseases from type 2 diabetes, arthritis, hypertension and to an extent, even cancer, and whose working has foxed international researchers may have been finally tamed at the Indian Institute of Science (IISc), Bangalore.
Inorganic Chemistry - The Next Generation
G. Mugesh has been recognized by the international journal Inorg. Chim. Acta in its special 40th anniversary edition "Inorganic Chemistry - The Next Generation".
Cover Page in Chemistry - A European Journal
The work on "Antibiotic Resistance - Functional Mimics of Metallo-beta-Lactamases" has been featured on the Cover Page of the Chemistry - A European Journal. This paper has also been listed as one of the Most Accessed articles in October 2006.
Cover Page in Organic & Biomolecular Chemistry
The work on "The Interaction of Anti-thyroid Drugs with Iodine" has been featured on the Cover Page of the journal Organic and Biomolecular Chemistry.
New Thyroid Drug - Down To Earth Magazine
Researchers from the Indian Institute of Science, Bangalore, have developed a drug against hyperthyroidsm, which, unlike other medication, has an effect that is reversible. G. Mugesh and his student, Gouriprasanna Roy, from the Institute's department of inorganic and physical chemistry, modified the antithyroid drug, methimazole, by replacing the sulfur by selenium.
Humboldt Foundation Equipment Award
G. Mugesh has received "AvH Equipment Award" from the Alexander von Humboldt Foundation, Germany. The award has been given by Mr Erwin Wendland, Consulate General of Federal Republic of Germany, during the AvH Association Annual Meeting at Indian Institute of Science.